Alexis Sanchez played a starring role as Chile beat Venezeula 3-1 on Tuesday to boost their World Cup qualification hopes.
Philippe Coutinho and Neymar scored as Brazil continued their march towards next year's World Cup in Russia with a dominant 3-0 win over Paraguay on Tuesday.
Spain beat France 2-0 at the Stade de France on Tuesday night in a friendly dominated by the intervention of the Video Assistant Referee.
An Argentina side reeling from the shock suspension of captain Lionel Messi crashed to a 2-0 defeat against Bolivia on Tuesday, dealing a fresh blow to their 2018 World Cup qualification campaign.
Cristiano Ronaldo scored but his Madeira homecoming ended in defeat as Portugal squandered a two-goal lead and conceded a late own goal against Sweden.
Italy beat the Netherlands 2-1 in a friendly on Tuesday in caretaker Dutch coach Fred Grim's first and possibly only match in charge.
Accrington Stanley maintain their hopes of a League Two play-off spot thanks to Shay McCartan's fourth goal in three games.
Republic of Ireland suffered their first home defeat in three years as Iceland reinforced their status as a growing European football force with a 1-0 victory in Dublin on Tuesday.