| Saturday 18th February 1978 | |||
| Arsenal | 4-1 | Walsall | |
| Bristol Rovers | 2-2 | Ipswich Town | |
| Leyton Orient | 0-0 | Chelsea | |
| Millwall | 2-1 | Notts County | |
| Queens Park Rangers | 1-1 | Nottingham Forest | |
| Wrexham | 1-1 | Blyth Spartans | |
| Wednesday 22nd February 1978 | |||
| Derby County | 2-3 | West Bromwich Albion | |
| Monday 27th February 1978 | |||
| Middlesbrough | 2-0 | Bolton Wanderers | |
| Replay | |||
| Blyth Spartans | 1-2 | Wrexham | (n) |
| Chelsea | 1-2 | Leyton Orient | |
| Nottingham Forest | 1-1 | Queens Park Rangers | aet |
| Tuesday 28th February 1978 | |||
| Replay | |||
| Ipswich Town | 3-0 | Bristol Rovers | |
| Thursday 2nd March 1978 | |||
| 2nd Replay | |||
| Nottingham Forest | 3-1 | Queens Park Rangers | |
