| Saturday 5th December 1992 | |||
| Accrington Stanley | 1-6 | Crewe Alexandra | (n) |
| Altrincham | 1-4 | Port Vale | |
| Bolton Wanderers | 4-0 | Rochdale | |
| Brighton and Hove A | 1-1 | Woking | |
| Burnley | 1-1 | Shrewsbury Town | |
| Cheltenham Town | 1-1 | Bournemouth | |
| Gillingham | 1-1 | Colchester United | |
| Macclesfield Town | 0-2 | Stockport County | |
| Marine | 3-2 | Stafford Rangers | |
| Reading | 3-0 | Leyton Orient | |
| Rotherham United | 1-0 | Hull City | |
| Yeovil Town | 0-0 | Hereford United | |
| Sunday 6th December 1992 | |||
| Bath City | 2-2 | Northampton Town | |
| Bradford City | 0-2 | Huddersfield Town | |
| Hartlepool United | 4-0 | Southport | |
| Wycombe Wanderers | 2-2 | West Bromwich Albion | |
| Wednesday 9th December 1992 | |||
| Plymouth Argyle | 3-2 | Peterborough United | |
| Rugby Town | 0-0 | Marlow | |
| Tuesday 15th December 1992 | |||
| Exeter City | 2-5 | Swansea City | |
| Wigan Athletic | 1-1 | Bury | |
| Replay | |||
| Northampton Town | 3-0 | Bath City | |
| Shrewsbury Town | 1-2 | Burnley | |
| West Bromwich Albion | 1-0 | Wycombe Wanderers | |
| Wednesday 16th December 1992 | |||
| Replay | |||
| Bournemouth | 3-0 | Cheltenham Town | |
| Colchester United | 2-3 | Gillingham | |
| Hereford United | 1-2 | Yeovil Town | |
| Marlow | 2-0 | Rugby Town | |
| Woking | 1-2 | Brighton and Hove A | |
| Saturday 2nd January 1993 | |||
| Replay | |||
| Bury | 1-0 | Wigan Athletic | |
