| Saturday 2nd January 1993 | |||
| Aston Villa | 1-1 | Bristol Rovers | |
| Blackburn Rovers | 3-1 | Bournemouth | |
| Brentford | 0-2 | Grimsby Town | |
| Brighton and Hove A | 1-0 | Portsmouth | |
| Derby County | 2-1 | Stockport County | |
| Gillingham | 0-0 | Huddersfield Town | |
| Hartlepool United | 1-0 | Crystal Palace | |
| Leeds United | 1-1 | Charlton Athletic | |
| Manchester City | 1-1 | Reading | |
| Newcastle United | 4-0 | Port Vale | |
| Oldham Athletic | 2-2 | Tranmere Rovers | |
| Sheffield United | 2-2 | Burnley | |
| Swansea City | 1-1 | Oxford United | |
| Tottenham Hotspur | 5-1 | Marlow | |
| Watford | 1-4 | Wolverhampton Wndrs | |
| West Bromwich Albion | 0-2 | West Ham United | |
| Wimbledon | 0-0 | Everton | |
| Yeovil Town | 1-3 | Arsenal | |
| Sunday 3rd January 1993 | |||
| Bolton Wanderers | 2-2 | Liverpool | |
| Nottingham Forest | 2-1 | Southampton | |
| Monday 4th January 1993 | |||
| Queens Park Rangers | 3-0 | Swindon Town | |
| Tuesday 5th January 1993 | |||
| Manchester United | 2-0 | Bury | |
| Tuesday 12th January 1993 | |||
| Crewe Alexandra | 3-1 | Marine | |
| Ipswich Town | 3-1 | Plymouth Argyle | |
| Northampton Town | 0-1 | Rotherham United | |
| Notts County | 0-2 | Sunderland | |
| Replay | |||
| Burnley | 2-4 | Sheffield United | |
| Everton | 1-2 | Wimbledon | |
| Oxford United | 2-2 | Swansea City | aet |
| (Swansea City won on penalties) | |||
| Tranmere Rovers | 3-0 | Oldham Athletic | |
| Wednesday 13th January 1993 | |||
| Cambridge United | 1-2 | Sheffield Wednesday | |
| Leicester City | 2-2 | Barnsley | |
| Middlesbrough | 2-1 | Chelsea | |
| Norwich City | 1-0 | Coventry City | |
| Southend United | 1-0 | Millwall | |
| Replay | |||
| Charlton Athletic | 1-3 | Leeds United | |
| Huddersfield Town | 2-1 | Gillingham | |
| Liverpool | 0-2 | Bolton Wanderers | |
| Reading | 0-4 | Manchester City | |
| Tuesday 19th January 1993 | |||
| Luton Town | 2-0 | Bristol City | |
| Wednesday 20th January 1993 | |||
| Replay | |||
| Barnsley | 1-1 | Leicester City | aet |
| (Barnsley won on penalties) | |||
| Bristol Rovers | 0-3 | Aston Villa | |
