Derby County's on-loan Manchester United striker James Wilson has sustained an anterior cruciate ligament injury.
Preview followed by live coverage of Saturday's Championship game between Sheffield Wednesday and Queens Park Rangers.
Sheffield Wednesday goalkeeper Keiren Westwood is an injury doubt for the home game against QPR.
Problems are mounting for Nottingham Forest head coach Philippe Montanier ahead of the visit of Cardiff.
Wigan will have on-loan pair Kyle Knoyle and Reece Burke available against Brighton at the DW Stadium.
Norwich are again expected to be without midfielder Jonny Howson for the Sky Bet Championship clash with Preston at Carrow Road.
Brentford can welcome back Harlee Dean from suspension for the visit of Barnsley.