Portsmouth boss Paul Cook still has automatic promotion hope from League Two while it remains mathematically possible.
Adrian Lopez's injury-time goal gave Villarreal a 1-0 victory over Liverpool in the Europa League semi-final first leg.
Sevilla stayed on course for a third consecutive Europa League crown after a 2-2 semi-final first leg draw at Shakhtar Donetsk.
Team news ahead of Saturdays Sky Bet League 2 clash between Leyton Orient and Mansfield
Team news ahead of Saturday's Sky Bet League 2 clash between Northampton and Luton
Team news ahead of Saturday's Sky Bet League 2 clash between Wycombe and Accrington Stanley
Leyton Orient midfielder Kevin Nolan is a doubt for the Sky Bet League Two game at home to Mansfield.
Wycombe will make a late decision on defender Danny Rowe ahead of Saturday's Sky Bet League Two game against Accrington.