| Saturday 21st November 1885 | |||
| English FA Cup Second Round | |||
| Blackburn Rovers | 1-0 | Oswaldtwistle Rovers | |
| Darwen Old Wanderers | 2-1 | Accrington | |
| Davenham | 8-1 | Macclesfield Town | |
| Derby Midland | 1-3 | Walsall Swifts | |
| Druids | 2-2 | Port Vale | aet |
| Gainsborough Trinity | 1-2 | Middlesbrough | |
| Grimsby Town | 8-0 | Darlington | |
| Long Eaton Rangers | 1-4 | Staveley | |
| Marlow | 6-1 | Old Etonians | |
| Nottingham Forest | 4-1 | Notts Olympic | |
| Notts County | 8-0 | Sheffield | |
| Old Carthusians | 6-0 | Upton Park | |
| Old Harrovians | 2-1 | Old Foresters | |
| Old Westminsters | 3-0 | Old Brightonians | |
| Old Wykehamists | 10-0 | Luton Wanderers | |
| Oswestry | 1-1 | Crewe Alexandra | |
| (Crewe Alexandra won - Oswestry disqualified) | |||
| Rawtenstall | 3-3 | Bolton Wanderers | |
| (Bolton Wanderers won - Rawtenstall disqualified) | |||
| Redcar | 2-0 | Lincoln Lindum | |
| Rossendale | 9-1 | Padiham | |
| Sheffield Heeley | 1-6 | Notts Rangers | |
| South Reading | 1-1 | Clapton | |
| (South Reading won - Clapton disqualified) | |||
| Swifts | 5-1 | Rochester | |
| West Bromwich Albion | 3-2 | Wednesbury Old Ath | |
| Wolverhampton Wndrs | 4-2 | Stafford Road | |
» Results : Saturday 21st November 1885
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