| Tuesday 2nd September 1980 | |||
| English League Cup Second Round 2nd Leg | |||
| Arsenal | 3-1 | Swansea City | (4-2) |
| Barnsley | 4-2 | Mansfield Town | aet (4-2) |
| Bristol City | 0-0 | Birmingham City | (1-2) |
| Bury | 1-0 | Newcastle United | aet (3-3) |
| (Bury won on away goals) | |||
| Charlton Athletic | 2-1 | Carlisle United | (4-2) |
| Coventry City | 1-0 | Manchester United | (2-0) |
| Crystal Palace | 2-1 | Bolton Wanderers | (5-1) |
| Gillingham | 1-2 | Blackburn Rovers | aet (1-2) |
| Ipswich Town | 3-0 | Middlesbrough | (4-3) |
| Liverpool | 4-0 | Bradford City | (4-1) |
| Luton Town | 1-1 | Reading | (3-1) |
| Notts County | 2-0 | Newport County | (3-1) |
| Portsmouth | 1-0 | Oldham Athletic | aet (3-3) |
| (Portsmouth won on away goals) | |||
| Sheffield Wednesday | 3-1 | Wimbledon | (4-3) |
| Swindon Town | 2-0 | Lincoln City | (3-1) |
| Watford | 7-1 | Southampton | aet (7-5) |
| West Ham United | 4-0 | Burnley | (6-0) |
| Wolverhampton Wndrs | 0-1 | Cambridge United | (1-4) |
| Scottish Division TwoTable » | |||
| Queen of the South | 1-1 | Alloa Athletic | |
» Results : Tuesday 2nd September 1980
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