Rayo Vallecano beat Almeria 2-0 with goals in either half to all but secure Primera Division survival for a fourth consecutive season, while Granada and Sevilla ended level.
Defender Diego Mainz scored at both ends as rivals Granada and Sevilla drew 1-1 at Estadio Los Carmenes.
Real Madrid have confirmed that Luka Modric has strained ligaments in his right knee and must now wait to see when the influential midfielder will be available again.
Manchester City have been alerted by the news that Real Madrid could be willing to sell Isco during the summer.
Welsh forward goes off after just five minutes of Real's match with Malaga, and could miss the Champions League quarter-final second leg against Atletico
• Bale and Luka Modric injured days before Champions League clash • Pair limp off field for treatment as Real Madrid beat Málaga 3-1 • Lionel Messi scores his 400th Barcelona goal, against Valencia Continue reading...
An Aduriz double inspired Athletic Bilbao to a 4-0 victory over Getafe in the late La Liga kick-off.