Second-half goals from Chris Porter and Sammie Szmodics give Colchester a win away at Wycombe.
At least three of the six players who have been sidelined for Wycombe could return in Saturday's Sky Bet League Two home clash with Colchester.
Colchester United are represented in the latest Football League team of the week that has been selected after this week's midweek action.
Gary Roberts' late second-half brace against Colchester earns Portsmouth their first win of the season.
Portsmouth boss Paul Cook has confirmed that Conor Chaplin will feature against Colchester as his side search for their first win of the 2016-17 Sky Bet League Two campaign.
Skipper Craig Disley is in line to return to Grimsby's starting XI against Leyton Orient after coming off the bench to score at Colchester on Tuesday following his recovery from a concussion sustained in pre-season.
Brennan Dickenson scores twice as Colchester resist a spirited Grimsby fightback to record their second successive win.
Colchester United are represented in the latest Football League team of the week that has been selected after this week's action.