| Monday 21st September 1992 | |||
| 1st Leg | |||
| Tottenham Hotspur | 3-1 | Brentford | |
| Tuesday 22nd September 1992 | |||
| 1st Leg | |||
| Arsenal | 1-1 | Millwall | |
| Bolton Wanderers | 1-3 | Wimbledon | |
| Bristol City | 2-1 | Sheffield United | |
| Bury | 0-0 | Charlton Athletic | |
| Cambridge United | 2-2 | Stoke City | |
| Carlisle United | 2-2 | Norwich City | |
| Crystal Palace | 3-1 | Lincoln City | |
| Exeter City | 0-1 | Oldham Athletic | |
| Leeds United | 4-1 | Scunthorpe United | |
| Liverpool | 4-4 | Chesterfield | |
| Notts County | 3-2 | Wolverhampton Wndrs | |
| Watford | 2-2 | Reading | |
| Wigan Athletic | 2-2 | Ipswich Town | |
| Wednesday 23rd September 1992 | |||
| 1st Leg | |||
| Blackpool | 0-4 | Portsmouth | |
| Brighton and Hove A | 1-1 | Manchester United | |
| Coventry City | 2-0 | Scarborough | |
| Gillingham | 0-0 | Southampton | |
| Huddersfield Town | 1-1 | Blackburn Rovers | |
| Leicester City | 2-0 | Peterborough United | |
| Luton Town | 2-2 | Plymouth Argyle | |
| Manchester City | 0-0 | Bristol Rovers | |
| Newcastle United | 0-0 | Middlesbrough | |
| Oxford United | 1-2 | Aston Villa | |
| Queens Park Rangers | 2-1 | Grimsby Town | |
| Rotherham United | 1-0 | Everton | |
| Sheffield Wednesday | 3-0 | Hartlepool United | |
| Southend United | 1-0 | Derby County | |
| Stockport County | 2-3 | Nottingham Forest | |
| Torquay United | 0-6 | Swindon Town | |
| Walsall | 0-3 | Chelsea | |
| West Ham United | 0-0 | Crewe Alexandra | |
| Tuesday 6th October 1992 | |||
| 2nd Leg | |||
| Blackburn Rovers | 4-3 | Huddersfield Town | aet (5-4) |
| Chesterfield | 1-4 | Liverpool | (5-8) |
| Grimsby Town | 2-1 | Queens Park Rangers | aet (3-3) |
| (Queens Park Rangers won on penalties) | |||
| Hartlepool United | 2-2 | Sheffield Wednesday | (2-5) |
| Ipswich Town | 4-0 | Wigan Athletic | (6-2) |
| Lincoln City | 1-1 | Crystal Palace | (2-4) |
| Peterborough United | 2-1 | Leicester City | (2-3) |
| Plymouth Argyle | 3-2 | Luton Town | (5-4) |
| Portsmouth | 2-0 | Blackpool | (6-0) |
| Swindon Town | 3-2 | Torquay United | (9-2) |
| Wimbledon | 0-1 | Bolton Wanderers | (3-2) |
| Wednesday 7th October 1992 | |||
| 2nd Leg | |||
| Aston Villa | 2-1 | Oxford United | (4-2) |
| Brentford | 2-4 | Tottenham Hotspur | (3-7) |
| Bristol Rovers | 1-2 | Manchester City | aet (1-2) |
| Charlton Athletic | 0-1 | Bury | (0-1) |
| Chelsea | 1-0 | Walsall | (4-0) |
| Crewe Alexandra | 2-0 | West Ham United | (2-0) |
| Derby County | 7-0 | Southend United | (7-1) |
| Everton | 3-0 | Rotherham United | (3-1) |
| Manchester United | 1-0 | Brighton and Hove A | (2-1) |
| Middlesbrough | 1-3 | Newcastle United | (1-3) |
| Millwall | 1-1 | Arsenal | aet (2-2) |
| (Arsenal won on penalties) | |||
| Norwich City | 2-0 | Carlisle United | (4-2) |
| Nottingham Forest | 2-1 | Stockport County | (5-3) |
| Oldham Athletic | 0-0 | Exeter City | (1-0) |
| Reading | 0-2 | Watford | (2-4) |
| Scarborough | 3-0 | Coventry City | (3-2) |
| Sheffield United | 4-1 | Bristol City | (5-3) |
| Southampton | 3-0 | Gillingham | (3-0) |
| Stoke City | 1-2 | Cambridge United | (3-4) |
| Wolverhampton Wndrs | 0-1 | Notts County | (2-4) |
| Tuesday 27th October 1992 | |||
| 2nd Leg | |||
| Scunthorpe United | 2-2 | Leeds United | (3-6) |
