| Wednesday 22nd October 1975 | |||
| 1st Leg | |||
| Benfica | 5-2 | Ujpesti Dozsa | |
| Borussia Monch'bach | 2-0 | Juventus | |
| Derby County | 4-1 | Real Madrid | |
| Dinamo Kiev | 3-0 | IA Akranes | |
| Hajduk Split | 4-0 | RWD Molenbeek | |
| Malmo | 1-0 | Bayern Munich | |
| Ruch Chorzow | 1-3 | PSV Eindhoven | |
| Saint-Etienne | 2-0 | Rangers | |
| Wednesday 5th November 1975 | |||
| 2nd Leg | |||
| Bayern Munich | 2-0 | Malmo | (2-1) |
| IA Akranes | 0-2 | Dinamo Kiev | (0-5) |
| Juventus | 2-2 | Borussia Monch'bach | (2-4) |
| PSV Eindhoven | 3-0 | Ruch Chorzow | (6-1) |
| Rangers | 1-2 | Saint-Etienne | (1-4) |
| Real Madrid | 5-1 | Derby County | (6-5) |
| RWD Molenbeek | 2-3 | Hajduk Split | (2-7) |
| Ujpesti Dozsa | 3-1 | Benfica | (5-6) |
