| Wednesday 27th August 2008 | |||
| Third Qualifying Round 2nd Leg | |||
| Arsenal | 4-0 | FC Twente Enschede | (6-0) |
| Atletico Madrid | 4-0 | Schalke 04 | (4-1) |
| BATE Borisov | 1-1 | Levski Sofia | (2-1) |
| Dinamo Kiev | 4-1 | Spartak Moscow | (8-2) |
| Dinamo Zagreb | 1-3 | Shakhtar Donetsk | (1-5) |
| FBK Kaunas | 0-2 | AaB Aalborg | (0-4) |
| FC Basle | 2-1 | Vitoria Guimaraes | (2-1) |
| Fenerbahce | 2-1 | Partizan Belgrade | (4-3) |
| Liverpool | 1-0 | Standard Liege | aet (1-0) |
| Marseille | 2-1 | SK Brann | (3-1) |
| Olympiakos | 1-0 | Anorthosis Famagusta | (1-3) |
| Slavia Prague | 0-0 | Fiorentina | (0-2) |
| Steaua Bucharest | 1-0 | Galatasaray | (3-2) |
| Tuesday 16th September 2008 | |||
| First Round Group A | |||
| Chelsea | v | Bordeaux | |
| Roma | v | CFR Cluj-Napoca | |
| First Round Group B | |||
| Panathinaikos | v | Inter Milan | |
| Werder Bremen | v | Anorthosis Famagusta | |
| First Round Group C | |||
| Barcelona | v | Sporting Lisbon | |
| FC Basle | v | Shakhtar Donetsk | |
| First Round Group D | |||
| Marseille | v | Liverpool | |
| PSV Eindhoven | v | Atletico Madrid | |